Board logo

標題: Dose-dependent adsorptive capacity of activated charcoal [打印本頁]

作者: sakurajunjun    時間: 2020-11-5 11:29     標題: Dose-dependent adsorptive capacity of activated charcoal

Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteersbulk pelletized activated charcoal

The amount of activated charcoal needed to treat drug overdoses has arbitrarily been set at a charcoal-drug ratio of 10:1. Recent in vitro studies have shown a larger adsorptive capacity for activated charcoal when used in a model of paracetamol overdose. In the present study, we investigated whether this reserve capacity exists in vivo. This is clinically relevant in cases of large overdoses or if the full standard dose of 50 g activated charcoal cannot be administered. We performed a randomized, cross-over study (n = 16). One hour after a standard breakfast, 50 mg/kg paracetamol was administered, followed 1 hr later by an activated charcoal-Water slurry containing 50 (control), 25 or 5 g activated charcoal. The areas under the serum concentration-time curve (AUC) for paracetamol were used to estimate the efficacy of each activated charcoal dose. The AUC of the 25-g dose was found to be of similar size compared to the control, although statistics were weak. The AUC of the 5-g dose was 59% larger than the AUC of the 50-g dose (p = 0.0003). The terminal elimination half-life (t(1/2)) of paracetamol was 1.6 (CI 1.4-2.0) and 1.9 (CI 1.5-2.4) hr for 50 and 25 g, respectively (NS), and 2.5 (CI 1.8-3.0) hr for the 5-g dose (p = 0.003). The decrease in t(1/2) of paracetamol for the two larger activated charcoal doses indicates a possible effect of activated charcoal on paracetamol clearance and warrants further investigation. The large adsorptive reserve capacity of activated charcoal in vitro could not be reproduced for the smallest dose of activated charcoal. An activated charcoal-drug ratio of 10:1 is therefore still recommendable.wanyang activated charcoal
作者: superhero2227    時間: 2020-11-9 16:34

必利勁
印度必利勁
超級必利勁
希愛力  
超級希愛力
液態威爾鋼
永春糖
必利吉  
印度樂威壯
汗馬糖  
雙效果凍  
印度卡瑪格咀嚼片   
艾力達  
超級艾力達
東革阿里咖啡
雙效威而鋼
威格拉
FWEFW
作者: twman19    時間: 2021-4-11 12:21

犀利士威而鋼一起吃可以嗎?   
樂威壯口溶錠效果怎麼樣?   
威而鋼各向異性有哪些?  
美國黑金提升性功能的三大功效你知道嗎?   
日本藤素可以治療陽痿早洩嗎?  
必利勁可以長期吃嗎?   
犀利士可以治療陽痿早洩嗎?   
威而鋼價格多少錢?  
日本藤素沒用是真的?   
超级希愛力是什麼?   
偉哥是什麼?  
美國黑金用法你知道嗎?   
犀利士價格多少錢?  
超級必利勁和必利勁有什麼不同的功效?  
藥局威而鋼有賣嗎?   
日本藤素可以每天吃嗎?  
犀利士副作用你知道嗎?  
藍色小藥丸是什麼?   
超級必利勁有什麼獨特功效?  
美國黑金比日本藤素效果更好嗎?   
威而鋼是春藥嗎?  

日本藤素可以每天吃嗎?   
美國黑金官網真的存在嗎?   
必利勁藥局有賣嗎?   
威而剛購買需要注意些什麼?   
犀利士的這些資訊你知道嗎?   
樂威壯口溶錠對性功能障礙有用嗎?   
日本藤素ptt分享   
威而鋼副作用有那些?   
必利勁台灣官網怎麼購買?   
威而鋼真偽如何分辨?   
犀利士學名藥是什麽?   
必利勁只有持久延時作用嗎?   
犀利士藥局有賣嗎?
作者: christian398    時間: 2021-6-16 21:27

powerpoint, 新竹福華飯店夏卡瓦, 邱素貞瑜珈費用, 盛發堂滷味有限公司, 衣架防塵罩, 京都賞楓時間, 中華職棒遊戲2, 90後極品小鮮肉, 開庭查詢, 泰山圖書館開放時間, 京都賞楓自由行行程, 白沙灣一日遊, 90後極品小嫩肉, 小楊桃食譜, 小學畢業旅行, 郭世倫部落格, 何謂12年國教優缺點, 台中+690+佳佳, 八三夭來去夏威夷mv, 台中泰式餐廳吃到飽, 台中690佳佳, 換剎車皮多少錢, 相片拼貼app, 台中魚訊佳佳, 李羅, 馥鴻科技待遇, yyets人人影視字幕組, 姐弟戀電影, 松香水msds, 全球快遞公司, mp870影片, 白吉勝付心漢, 保衛釣魚島, 青少年心理學題庫, 樂天超市必買2013, 女王部落格曼谷, 熱呼呼毛毯, 亞麻油黑肥皂價格, 伊斯克萊吸塵器, 花粉的功效副作用, 官網設計, 2008東京自由行blog, 五月天聖誕夜驚魂, 九年國教優缺點, 正薪醫院小兒科, 母子戀文章,....................................................................................................

....................................................................................................
懷孕前健康檢查項目, 酒糟皮膚保養品, 酒糟保養, 翁鬱容學歷, 軍人福利網, 膠囊旅館台北, 庫洛姆圖片, 海口現撈, 高雄雷射除毛推薦, 夜店最新




歡迎光臨 game high遊戲論壇 (http://ww.w.uflashgame.com/discuz/) Powered by Discuz! 7.0.0